А.М. MUTAN ¹

1. «Karaganda medical university» NPJSC, Karaganda, the Republic of Kazakhstan

DOI: https://www.doi.org/10.52532/2663-4864-2023-3-69-79-85

UDC: 616.34-006.6-036:084(574.31)

Year: 2023 issure: 69 number: 3 pages: 79-85

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ABSTRACT

Relevance: Colorectal cancer (CRC) is the leading cancer in yearly morbidity and mortality. WHO forecasts that 2030 CRC incidence will exceed 2.2 million cases yearly, and mortality will increase to 1.1 million yearly. More than 3,000 new cases of colorectal cancer are detected annually in Kazakhstan. In disease control, it is necessary to develop preventive measures as much as possible. Preventive measures play a crucial role in reducing mortality from this disease. One of the most critical issues is the lack of public awareness about the disease.
The study analyzes the global experience in preventing colorectal cancer to develop measures to raise public awareness.
Methods: A continuous search was performed in the PubMed, CrossRe, Scopus, and Cochrane databases for 2013-2023 for the keywords “colorectal cancer,” “risk factors,” “public awareness,” “medical literacy,” “morbidity,” and “prevention.” In total, more than 75 scientific articles and 500 abstracts were reviewed.
Results: The problem is aggravated by the fact that among patients with an oncological diagnosis, patients with colorectal cancer, or patients with a confirmed diagnosis of the disease, there is insufficient information about this disease, and they neglect preventive measures. Firstly, we insist that the population is not fully aware of the responsibility for their health (this is influenced by a false sense of shame and insufficient awareness of the disease), and secondly, primary prevention is essential. Accordingly, it is necessary to increase the effectiveness of screening programs, improve awareness, and organize full-fledged assistance from the state in disease control.
Conclusion: Colorectal cancer is an urgent disease that occupies an essential place in Kazakhstan’s list of oncological diseases. Due to the increased awareness of the population about this disease and the correct solution to prevention issues, it will be possible to reduce the incidence among patients. In this regard, it is necessary to widely disseminate information about the disease among the population and increase patients’ responsibility for their health.
Keywords: colorectal cancer, risk factors, public awareness, medical literacy, morbidity, prevention.

List of sources used:

1. Wong M.C.S., Huang J., Lok V., Wang J., Fung F., Ding H., Zheng Z.J. Differences in Incidence and Mortality Trends of Colorectal Cancer Worldwide Based on Sex, Age, and Anatomic Location. Clin // Gastroenterol. Hepatol. – 2020. https://doi.org/10.1016/j.cgh.2020.02.026.
2. Жылкайдарова А.Ж., Хегай Б.С., Джуманов А.И., Горбунова Н.С., Арстамбаева С.С. Оценка информированности населения города Алматы о скрининге колоректального рака // Сб. тезисов VIII съезда онкологов и радиологов Казахстана с межд. уч. – 14-16 октября 2021 года, г. Туркестан. – Онкология и радиология Казахстана. – Спецвыпуск. – 2021. – С. 9 [Zhylkajdarova A.Zh. Hegaj B.S., Dzhumanov A.I., Gorbunova N.S., Arstambaeva S.S. Ocenka informirovannosti naselenija goroda Almaty o skrininge kolorektal’nogo raka // Сб. тезисов VIII съезда онкологов и радиологов Казахстана с межд. уч. – 14-16 октября 2021 года, г. Туркестан. – Онкология и радиология Казахстана. – Спецвыпуск. – 2021. – С. 9 (in Russ.)] https://oncojournal.kz/docs/archive/10.52532-2521-6414-2021-14-1610-VIII-congress-of-oncologists-radiologists-of-kazakhstan.pdf
3. Murray C.J.L. GBD 2015 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 79 behavioral, environmental, occupational, and metabolic risks or clusters of risks, 2000–2015: a systematic analysis for the Global Burden of Disease Study 2015 // Lancet. – 2016. – Vol. 388 (10053). – P. 1659-1724. https://doi.org/10.1016/S0140-6736(16)31679-8
4. Plummer M., De Martel C., Vignat J., Ferlay J., Bray F., Franceschi S. Global burden of cancers attributable to infections in 2015: a synthetic analysis // Lancet Glob. Health. – 2016. – Vol. 4(9). – P. e609-e616. https://doi.org/10.1016/S2214-109X(16)30143-7
5. Bray F., Ferlay J., Soerjomataram I. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries // CA Cancer J Clin. – 2018. – Vol. 68. – P. 394–424.
6. Arnold M., Sierra M.S., Laversanne M., Soerjomataram I., Jemal A., Bray F. Global patterns and trends in colorectal cancer incidence and mortality // Gut. – 2017. – Vol. 66(4). – P. 683-691. https://doi.org/10.1136/gutjnl-2015-310912
7. El Zoghbi M., Cummings L.C. New era of colorectal cancer screening // World J. Gastrointest. Endosc. – 2016. – Vol. 8(5) – P. 252-258. https://doi.org/10.4253/wjge.v8.i5.252
8. Никонов Е.Л. Применение фекальных тестов в программах скрининга колоректального рака // Доктор.Ру. – 2018. – №3(147). – С. 16-22. [Nikonov E.L. Primenenie fekal’nykh testov v programmakh skrininga kolorektal’nogo raka // Doktor.ru. – 2018. – №3(147). – С. 16-22. (in Russ.)] https://doi.org/10.31550/1727-2378-2019-165-10-23
9. Ferlay J., Ervik M., Lam F. Global Cancer Observatory: Cancer Today. Lyon, France: International Agency for Research on Cancer. – 2020. http://gco.iarc.fr/today/data/factsheets/cancers/10_8_9-Colorectum-fact-sheet.pdf
10. Al-Hajeili M., Abdulwassi H.K., Alshadadi F., Alqurashi L., Idriss M., Halawani L. Assessing knowledge on preventive colorectal cancer screening in Saudi Arabia: a cross-sectional study // J. Fam. Med. Prim. Care. – 2019. – Vol. 8(10). – P. 3140-3146. https://www.researchgate.net/publication/336893489_Assessing_knowledge_on_preventive_colorectal_cancer_screening_in_Saudi_Arabia_A_cross-sectional_study
11. Medhin L.B., Achila O.O., Abraham A.T. Incidence of colorectal cancer in Eritrea: data from the National Health Laboratory, 2011-2017 // PloS One. – 2019. – Vol. 14(11). – P. e0224045. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0224045
12. U.S. Preventive Services Task Force, Bibbins-Domingo K., Grossman D.C., Curry S.J., Davidson K.W., Epling J.W. Screening for colorectal cancer: U.S. Preventive Services Task Force recommendation statement // JAMA. – 2016. – Vol. 315. – P. 2564–2575. https://jamanetwork.com/journals/jama/fullarticle/2529486
13. Ханевич М.Д., Хазов А.В., Хрыков Г.Н., Меджидов О.А. Факторы риска и профилактика колоректального рака // Профилакт. Мед. – 2019. – №22(3). – С. 107-111. [Hanevich M.D., Hazov A.V., Hrykov G.N., Medzhidov O.A. Faktory riska i profilaktika kolorektal’nogo raka // Profilakt. Med. – 2019. – №22(3). – S. 107-111. (in Russ.)]. https://doi.org/10.17116/profmed201922031107
14. Hossain M.S., Karuniawati H., Jairoun A.A., Urbi Z., Ooi D.J., John A., Lim, Y.C., Kibria K.M.K., Mohiuddin A.M., Ming L.C. Colorectal Cancer: A Review of Carcinogenesis, Global Epidemiology, Current Challenges, Risk Factors, Preventive and Treatment Strategies // Cancers. – 2022. – Vol. 14. – P. 1732. https://doi.org/10.3390/cancers14071732
15. Helsingen L.M., Kalager M. Colorectal cancer screening – approach, evidence, and future directions // N. Engl J. Med Evid. – 2022. – Vol. 1(1). https://doi.org/10.1056/EVIDra2100035
16. Кашин С.В., Нехайкова Н.В., Завьялов Д.В., Видяева Н.С., Белова А.Н. Скрининг колоректального рака: общая ситуация в мире и рекомендованные стандарты качества колоноскопии // Доказат. гастроэнтерол. – 2017. – №4. – С. 32-52. [Kashin S.V., Nekhajkova N.V., Zav’yalov D.V., Vidyaeva N.S., Belova A.N. Skrining kolorektal’nogo raka: obshchaya situaciya v mire i rekomendovannyestandarty kachestva kolonoskopii // Dokazat. Gastroenterol. – 2017. – №4. – S. 32-52. (in Russ.)] https://doi.org/10.17116/dokgastro20176432-52
17. Grancher A., Michel P., Fiore F., Sefrioui D. Aspirine et colorectal cancer // Bull Cancer. –2018. – Vol. 105(2). – P. 171-180. https://doi.org/10.1016/j.bulcan.2017.09.013
18. Жадыкова Е.Н., Саханов С.Б., Туребаев Д.К., Кульмирзаева Д.М., Уразова С.Н., Аманшаева А.К., Билялова З.А., Кожахметов С.К., Игисинов Н.С. Изменения показателей онкологической службы при колоректальном раке в Восточно-Казахстанской области // Медицина (Алматы). – 2020. – №9-10 (219-220). – С. 11-16 [Zhadykova E.N., Sahanov S.B., Turebaev D.K., Kul’mirzaeva D.M., Urazova S.N., Amanshaeva A.K., Bilyalova Z.A., Kozhahmetov S.K., Igisinov N.S. Izmeneniya pokazatelej onkologicheskoj sluzhby pri kolorektal’nom rake v Vostochno-Kazahstanskoj oblasti // Medicina (Almaty). – 2020. – №9-10 (219-220). – S. 11-16. (in Russ.)]. https://doi.org/10.31082/1728-452X-2020-219-220-9-10-11-16
19. Lauby-Secretan B., Vilahur N., Bianchini F., Guha N., Straif K. International Agency for Research on Cancer Handbook Working Group. The IARC Perspective on Colorectal Cancer Screening // N. Engl J. Med. – 2018. – Vol. 378(18). – P. 1734-1740. https://doi.org/10.1056/NEJMsr1714643
20. Шут С.А., Платошкин В.Э., Платошкина Т.В., Никулина Н.А., Николаева Н.В. Инновационные подходы к профилактике колоректального рака // Пробл. Здор. Экол. – 2022. – №19(1). – C. 13-20 [Shut S.A., Platoshkin V.E., Platoshkina T.V., Nikulina N.A., Nikolaeva N.V. Innovacionnye podhody k profilaktike kolorektal’nogo raka // Probl. Zdor. Ekol. – 2022. – №19(1). – S. 13-20. (in Russ.)] https://doi.org/10.51523/2708-6011.2022-19-1-02
21. Adamina M., Bonovas S., Raine T., Spinelli A., Warusavitarne J., Armuzzi A. European Crohn’s and Colitis Organisation [ECCO], ECCO Guidelines on Therapeutics in Crohn’s Disease: Surgical Treatment // JCC. – 2020. – Vol. 14(2). – P. 155-168. https://doi.org/10.1093/ecco-jcc/jjz187
22. Patel S.G., Karlitz J.J., Yen T., Lieu C.H., Boland C.R. The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection // Lancet. – 2022. – Vol. 7(3). – P. 262-274. https://doi.org/10.1016/S2468-1253(21)00426-X
23. Юсупова Н.З., Гиниятуллина Л.А. Анализ современных представлений о роли различных факторов риска в развитии колоректального рака (обзор литературы) // Вест. Нов. Мед. Техн. – 2020. – №27(4). – C. 5-10. [Yusupova N.Z., Giniyatullina L.A. Analiz sovremennyh predstavlenij o roli razlichnyh faktorov riska v razvitii kolorektal’nogo raka (obzor literatury) // Vestn. Nov. Med. Tekhn. – 2020. – №27(4). – S. 5-10. (in Russ.)]. https://doi.org/10.24411/1609-2163-2020-16698
24. American Cancer Society. Colorectal cancer. Facts & Figures 2020-2022.. 26.06.2023.
25. Kanth P., Inadomi J.M. Screening and prevention of colorectal cancers // BMJ. – 2021. – Vol. 374. – Art. no. n1855. https://doi.org/10.1136/bmj.n1855
26. Xi Y., Xu P. Global colorectal cancer burden in 2020 and projections to 2040 // Transl. Oncol. – 2021. – Vol. 14(10). – Art. no. 101174. https://doi.org/10.1016/j.tranon.2021.101174
27. Ahmed I., Kamara M., Kassem W., Hamdy M., Nabeel M., Salam D., Salam Y., Ewbank F. Quality Assurance of Flexible Sigmoidoscopy as a Screening Tool for Colorectal Cancer // J. Clin. Gastroenterol. Hepatol. – 2018. – Vol. 2(1). – P. 9. https://www.primescholars.com/articles/quality-assurance-of-flexible-sigmoidoscopy-as-a-screening-tool-for-colorectal-cancer-93961.html
28. Eklöv K., Nygren J., Bringman S., Trends in the treatment of colorectal cancer and short-term outcomes during the first wave of the COVID-19 pandemic in Sweden // JAMA Netw. Open. – 2022. – Vol. 5(5). – Art. no. e2211065. https://doi.org/10.1001/jamanetworkopen.2022.11065
29. Ao T., Kajiwara Y., Yamada K. Cancer-induced speculation on computed tomography: a significant preoperative prognostic factor for colorectal cancer // Surg. Today. – 2019. – Vol. 49(7). – P. 629-636. https://doi.org/10.1007/s00595-019-01780-2
30. Afshari K., Chabok A., Naredi P., Smedh K., Nikberg M. Prognostic factors for survival in stage IV rectal cancer: a Swedish nationwide case-control study // Surg. Oncol. – 2019. – Vol. 29. – P. 102-106. https://doi.org/10.1016/j.suronc.2019.04.005