Improved patient functioning after treatment of breakthrough cancer pain: an open-label study of fentanyl buccal tablet in patients with cancer pain

Improved patient functioning after treatment of breakthrough cancer pain: an open-label study of fentanyl buccal tablet in patients with cancer pain

JAROSZ J..1 , MERCADANTE S..2 , POULAIN P..3 , O’BRIEN T..4 , SCHNEID H..5 , KRESS H.G.6

1. Mossakowski Медицинский научно-исследовательский центр Польской академии наук, Варшава, Польша
2. Casa di Cura di Alta Specialità, La Maddalena, Terapia del Dolore e Cure Palliative, Palermo, Italy
3. Polyclinique de l’Ormeau, Tarbes, France
4. Department of Palliative Medicine, Marymount Hospice and Cork University Hospital, Cork, Ireland
5. Teva Laboratoires, La Défense, France
6. Department of Special Anaesthesia and Pain Therapy, Medical University/AKH , Vienna, Austria

Тип: Паллитивная помощь

УДК:

Год: 2016 выпуск: 41 номер: 3 страницы: 127-133

Реферат: Purpose This open-label study evaluated the effects of fentanyl buccal tablet (FBT) on functioning and mood in cancer patients with breakthrough cancer pain (BT cP). Methods Opioid-tolerant patients in seven European countries with up to four BT cP episodes/day received FBT doses (100– 800 μg) identified during open-label titration to treat up to eight BT cP episodes during an open-label treatment period. In countries where FBT was not commercially available, patients could enter an open-label continuation phase. Functionality and satisfaction assessments included change from baseline to the end of the treatment period in the modified Brief Pain Inventory (BP I-7S) seven-item interference subscale, patient’s global assessment of satisfaction and ease of use, and Patient’s Global Impression of Change (PG IC). Safety was also assessed.

Скачать PDF: 2016.3.41_03.pdf

Ключевые слова: break through pain, chronic pain, fentanyl buccal tablet, opioid analgesic, pain management, cancer patients

Ссылка: Jarosz J.. , Mercadante S.. , Poulain P.. , O’brien T.. , Schneid H.. , Kress H.G. Improved patient functioning after treatment of breakthrough cancer pain: an open-label study of fentanyl buccal tablet in patients with cancer pain. Онкология и радиология Казахстана, 2016, 41 (3), 127-133.

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