B.I. Imasheva¹, М.А. Kamaliev¹, V.N. Lokshin², A.S. Shinbolatova³, M.V. Kiseleva⁴, A.D. Turekhanova⁵, A.E. Jexembekova⁵

1. Kazakhstan’s Medical University «Higher School of Public Health» LLP, Almaty, the Republic of Kazakhstan;
2. International Clinical Center for Reproductology «Persona» LLP, Almaty, the Republic of Kazakhstan;
3. «Kazakh Institute of Oncology and Radiology» JSC, Almaty, the Republic of Kazakhstan;
4. Medical Radiological Research Center named after A.F. Tsyba – branch of the Federal State Budgetary Institution «NMIC of Radiology» of the Ministry of Health of the Russian Federation, Obninsk, Russian Federation;
5. «Al-Farabi Kazakh National University» NCJSC, Almaty, the Republic of Kazakhstan

DOI: https://www.doi.org/10.52532/2521-6414-2024-1-71-4-11

UDC: 616-006.-076.5

Year: 2024 issure: 71 number: 1 pages: 4-11

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ABSTRACT

Relevance: Cancer of the uterine body (CUB) is one of the most common types of malignant neoplasms and ranks 6th among the most frequently diagnosed cancers in women in the world. Despite the improvement of treatment methods, the incidence and mortality from CUB remain high. According to forecasts by the International Agency for Research on Cancer, by 2040, the incidence of CUB is expected to increase by more than 50%. Therefore, studying the epidemiological features of CUB is important for developing prevention and treatment strategies.
The study aimed to analyze the morbidity and mortality from CUB in the female population of Almaty in 2012-2022.
Methods: The material for the study was data from the information system «Electronic Register of Inpatient Patients» on newly identified cases and those registered at the dispensary with a histologically confirmed diagnosis of CUB «Malignant neoplasm of the uterine body» (From 54 to ICD-10) of the population of Almaty for the period from 2012 to 2022. Epidemiological indicators were calculated per 100,000 female population. The absolute growth, growth rate, and visibility indicators were calculated to analyze changes in intensive indicators over time. The database was formed, and the results were statistically processed using Microsoft Excel and the SPSS Statistics 26 statistical package.
Results: There was an increase in the crude incidence of CUB in the female population of Almaty in 2012-2022 by 3.14 times. The incidence of CUB increased with age, where the peak incidence was noted in the age group of 60-64 years (58.9±8.68 cases per 100,000 female population 95% CI = 39.5-78.2). Mortality from CUB decreased from 13.5 cases in 2012 to 1.3 cases per 100,000 female population in 2022 (10.4 times).
Conclusion: The conducted epidemiological analysis showed the need for further detailed study of the risk factors contributing to the occurrence of CUB and improvement of the activities of health services, starting from the primary health care level.
Keywords: uterine body cancer, morbidity, mortality, prevention, early diagnosis, morphological verification.

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