A.O. MURZAKHMETOVA ¹, A.M. MEIRAMOVA ¹, A.A. ISSILBAYEVA ¹, B.B. ABDAHINA ¹, E.T. OMRALINA ¹, B.A. AINABEKOVA ^1,2

1. “Astana Medical University” NCJSC, Astana, the Republic of Kazakhstan;
2. “National Research Oncology Center” LLP, Astana, the Republic of Kazakhstan

DOI: https://www.doi.org/10.52532/2663-4864-2023-1-67-46-49

UDC: 616.155.392-036.11+089.819.843-61:053.9

Year: 2023 issure: 67 number: 1 pages: 46-49

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ABSTRACT

Relevance: Kidney functions in treating acute myeloblastic leukemia (AML) undergo serious effects, especially in elderly patients. Chemotherapeutic drugs used to prepare for hematopoietic stem cell transplantation (HSCT) inevitably affect elderly patients’ kidney function. Moreover, involutive changes in the kidneys can physiologically decrease kidney function.
The study aimed to evaluate kidney function in an elderly patient with AML after HSCT.
Methods: The article describes a clinical case of AML in an elderly patient who underwent allogeneic HSCT.
Results: We analyzed the dynamics of the functional state from the moment of registration of AML to +100 days after HSCT. During the entire follow-up period, we did not detect any renal dysfunction in the elderly patient. Despite the HSCT and the effects of nephrotoxic drugs in an elderly patient + 100 days after HSCT, kidney function was preserved.
Conclusion: The described case highlights the importance of maintaining renal function in elderly patients after HSCT and long-term renal monitoring.
Keywords: hematopoietic stem cell transplantation (HSCT), bone marrow transplantation, acute myeloblastic leukemia (AML), renal failure, case report, glomerular filtration rate, complications, elderly patients.

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